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Association of Acquired and Heritable Factors With Intergenerational Differences in Age at Symptomatic Onset of Alzheimer Disease Between Offspring and Parents With Dementia

IMPORTANCE: Acquired and heritable traits are associated with dementia risk; however, how these traits are associated with age at symptomatic onset (AAO) of Alzheimer disease (AD) is unknown. Identifying the associations of acquired and heritable factors with variability in intergenerational AAO of...

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Detalles Bibliográficos
Autores principales: Day, Gregory S., Cruchaga, Carlos, Wingo, Thomas, Schindler, Suzanne E., Coble, Dean, Morris, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806434/
https://www.ncbi.nlm.nih.gov/pubmed/31617930
http://dx.doi.org/10.1001/jamanetworkopen.2019.13491