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Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans
BACKGROUND: Epigenetic age acceleration, a measure of biological aging based on DNA methylation, is associated with cardiovascular mortality. However, little is known about its relationship with hypertensive target organ damage to the heart, kidneys, brain, and peripheral arteries. METHODS: We inves...
Autores principales: | Smith, Jennifer A., Raisky, Jeremy, Ratliff, Scott M., Liu, Jiaxuan, Kardia, Sharon L. R., Turner, Stephen T., Mosley, Thomas H., Zhao, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806502/ https://www.ncbi.nlm.nih.gov/pubmed/31640709 http://dx.doi.org/10.1186/s12920-019-0585-5 |
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