Successful repair of a popliteal aneurysm with saphenous vein graft in a patient with Marfan syndrome

Marfan syndrome is an autosomal dominant disorder caused by mutations in the fibrillin 1 gene (FBN1). This leads to defective elasticity of connective tissue in the arterial wall. Aortic aneurysms and dissections are the most common vascular anomalies; the incidence of peripheral artery aneurysms is not well understood. Treatment options for infrainguinal disease are limited as endovascular interventions are generally contraindicated. The best conduit for arterial reconstruction is also unknown because there is concern that saphenous vein may become aneurysmal. Currently, there are few case reports regarding outcomes of infrainguinal arterial reconstructions, and follow-up has been very short term. We report a rare case of successful repair of a popliteal aneurysm using a saphenous vein graft in a patient with Marfan syndrome.