The ‘Finnish new variant of Chlamydia trachomatis’ escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019

The ‘Finnish new variant of Chlamydia trachomatis’ (FI-nvCT), escaping detection in the Aptima Combo 2 assay (AC2), is widespread across Norway. From June to August 2019, 84% (81/97) of available AC2/Aptima CT discordant samples from five laboratories were confirmed as FI-nvCT. Two additional CT var...

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Autores principales: Johansen, Tone Bjordal, Kløvstad, Hilde, Rykkvin, Rikard, Herrfurth-Erichsen, Einar Bredo, Sorthe, Joakim, Njølstad, Gro, Ebbesen, Marit Helen, Nygaard, Randi Monsen, Sandmoen, Ellen Kristin, Thilesen, Carina, Onken, Annette, Liljedal, Inger, Hadad, Ronza, Unemo, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2019
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807255/
https://www.ncbi.nlm.nih.gov/pubmed/31640843
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.42.1900592
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author Johansen, Tone Bjordal
Kløvstad, Hilde
Rykkvin, Rikard
Herrfurth-Erichsen, Einar Bredo
Sorthe, Joakim
Njølstad, Gro
Ebbesen, Marit Helen
Nygaard, Randi Monsen
Sandmoen, Ellen Kristin
Thilesen, Carina
Onken, Annette
Liljedal, Inger
Hadad, Ronza
Unemo, Magnus
author_facet Johansen, Tone Bjordal
Kløvstad, Hilde
Rykkvin, Rikard
Herrfurth-Erichsen, Einar Bredo
Sorthe, Joakim
Njølstad, Gro
Ebbesen, Marit Helen
Nygaard, Randi Monsen
Sandmoen, Ellen Kristin
Thilesen, Carina
Onken, Annette
Liljedal, Inger
Hadad, Ronza
Unemo, Magnus
author_sort Johansen, Tone Bjordal
collection PubMed
description The ‘Finnish new variant of Chlamydia trachomatis’ (FI-nvCT), escaping detection in the Aptima Combo 2 assay (AC2), is widespread across Norway. From June to August 2019, 84% (81/97) of available AC2/Aptima CT discordant samples from five laboratories were confirmed as FI-nvCT. Two additional CT variants (CT 23S rRNA C1514T and G1523A) also escaped AC2 detection. The high FI-nvCT proportion might indicate a long-term national spread and it cannot be excluded that FI-nvCT emerged in Norway.
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spelling pubmed-68072552019-11-07 The ‘Finnish new variant of Chlamydia trachomatis’ escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019 Johansen, Tone Bjordal Kløvstad, Hilde Rykkvin, Rikard Herrfurth-Erichsen, Einar Bredo Sorthe, Joakim Njølstad, Gro Ebbesen, Marit Helen Nygaard, Randi Monsen Sandmoen, Ellen Kristin Thilesen, Carina Onken, Annette Liljedal, Inger Hadad, Ronza Unemo, Magnus Euro Surveill Rapid Communication The ‘Finnish new variant of Chlamydia trachomatis’ (FI-nvCT), escaping detection in the Aptima Combo 2 assay (AC2), is widespread across Norway. From June to August 2019, 84% (81/97) of available AC2/Aptima CT discordant samples from five laboratories were confirmed as FI-nvCT. Two additional CT variants (CT 23S rRNA C1514T and G1523A) also escaped AC2 detection. The high FI-nvCT proportion might indicate a long-term national spread and it cannot be excluded that FI-nvCT emerged in Norway. European Centre for Disease Prevention and Control (ECDC) 2019-10-17 /pmc/articles/PMC6807255/ /pubmed/31640843 http://dx.doi.org/10.2807/1560-7917.ES.2019.24.42.1900592 Text en This article is copyright of the authors or their affiliated institutions, 2019. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Johansen, Tone Bjordal
Kløvstad, Hilde
Rykkvin, Rikard
Herrfurth-Erichsen, Einar Bredo
Sorthe, Joakim
Njølstad, Gro
Ebbesen, Marit Helen
Nygaard, Randi Monsen
Sandmoen, Ellen Kristin
Thilesen, Carina
Onken, Annette
Liljedal, Inger
Hadad, Ronza
Unemo, Magnus
The ‘Finnish new variant of Chlamydia trachomatis’ escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019
title The ‘Finnish new variant of Chlamydia trachomatis’ escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019
title_full The ‘Finnish new variant of Chlamydia trachomatis’ escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019
title_fullStr The ‘Finnish new variant of Chlamydia trachomatis’ escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019
title_full_unstemmed The ‘Finnish new variant of Chlamydia trachomatis’ escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019
title_short The ‘Finnish new variant of Chlamydia trachomatis’ escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019
title_sort ‘finnish new variant of chlamydia trachomatis’ escaping detection in the aptima combo 2 assay is widespread across norway, june to august 2019
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807255/
https://www.ncbi.nlm.nih.gov/pubmed/31640843
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.42.1900592
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