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A reduced form of nicotinamide riboside defines a new path for NAD(+) biosynthesis and acts as an orally bioavailable NAD(+) precursor
OBJECTIVE: A decay in intracellular NAD(+) levels is one of the hallmarks of physiological decline in normal tissue functions. Accordingly, dietary supplementation with NAD(+) precursors can prevent, alleviate, or even reverse multiple metabolic complications and age-related disorders in diverse mod...
Autores principales: | Giroud-Gerbetant, Judith, Joffraud, Magali, Giner, Maria Pilar, Cercillieux, Angelique, Bartova, Simona, Makarov, Mikhail V., Zapata-Pérez, Rubén, Sánchez-García, José L., Houtkooper, Riekelt H., Migaud, Marie E., Moco, Sofia, Canto, Carles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807296/ https://www.ncbi.nlm.nih.gov/pubmed/31767171 http://dx.doi.org/10.1016/j.molmet.2019.09.013 |
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