Synthesis, activity and mechanism of alkoxy-, carbamato-, sulfonamido-, thioureido-, and ureido-derivatives of 2,4,5-trimethylpyridin-3-ol against inflammatory bowel disease

Inflammatory bowel disease (IBD) is a chronic immuno-inflammation in gastrointestinal tract. We have evaluated the activity of the compounds to inhibit the adhesion of monocytes to colon epithelial cells is triggered by a pro-inflammatory cytokine, tumour necrosis factor (TNF)-α. The in vitro activi...

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Detalles Bibliográficos
Autores principales: Chaudhary, Chhabi Lal, Gurung, Pallavi, Jang, Seoul, Banskota, Suhrid, Nam, Tae-Gyu, Kim, Jung-Ae, Jeong, Byeong-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807866/
https://www.ncbi.nlm.nih.gov/pubmed/31619080
http://dx.doi.org/10.1080/14756366.2019.1677637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807866/
https://www.ncbi.nlm.nih.gov/pubmed/31619080
http://dx.doi.org/10.1080/14756366.2019.1677637

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