Cargando…
2904. Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice
BACKGROUND: Zika virus (ZIKV) caused an epidemic of microcephaly and congenital malformations in 2015–2016, prompting the development of ZIKV vaccines. Plasmid DNA and modified mRNA lipid nanoparticle-encapsulated (mRNA-LNP) vaccines were among the first to reach human clinical trials, where their e...
Autores principales: | Jagger, Brett W, Dowd, Kimberly A, Chen, Rita, Desai, Pritesh, Himansu, Sunny, Graham, Barney S, Pierson, Theodore C, Diamond, Michael S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808673/ http://dx.doi.org/10.1093/ofid/ofz359.182 |
Ejemplares similares
-
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
por: Shan, Chao, et al.
Publicado: (2017) -
Animal Models of Zika Virus Infection during Pregnancy
por: Caine, Elizabeth A., et al.
Publicado: (2018) -
Complete and de novo assembly of the Leishmania braziliensis (M2904) genome
por: la Fuente, Sandra González-de, et al.
Publicado: (2018) -
A VSV-based Zika virus vaccine protects mice from lethal challenge
por: Emanuel, Jackson, et al.
Publicado: (2018) -
An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections
por: VanBlargan, Laura A., et al.
Publicado: (2018)