Cargando…

1724. Plasmid-free CRISPR-Cas9 System for Genetic Engineering of Rhizopus delemar

BACKGROUND: Mucormycosis is a serious infection caused by fungi of the order Mucorales. Rhizopus delemar is the most common etiologic agent of mucormycosis. Pathogenesis studies of mucormycosis have been hampered by poor genetic trackability of the organism, owing to rare chromosomal integration eve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Yiyou, Baldin, Clara, Gebremariam, Teklegiorgis, Alqarihi, Abdullah, Mamouei, Zeinab, Wang, Ping, Nagy, Gabor, Skory, Christopher, Ibrahim, Ashraf S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808715/ http://dx.doi.org/10.1093/ofid/ofz360.1587

Ejemplares similares

Optimization of the CRISPR/Cas9 System to Manipulate Gene Function in Rhizopus delemar
por: Baldin, Clara, et al.
Publicado: (2017)

726. APX001 (Fosmanogepix) Is Effective in an Immunosuppressed Mouse Model of Rhizopus oryzae Infection
por: Gebremariam, Teklegiorgis, et al.
Publicado: (2019)

APX001A Protects Immunosuppressed Mice from Rhizopus delemar Infection
por: Gebremariam, Teclegiorgis, et al.
Publicado: (2017)

678. Galactomannan Is a Biomarker of APX001 (Fosmanogepix) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis
por: Gebremariam, Teklegiorgis, et al.
Publicado: (2019)

The Role of Aquaporins in pH-Dependent Germination of Rhizopus delemar Spores
por: Turgeman, Tidhar, et al.
Publicado: (2016)

Targeted Delivery of Antifungal Liposomes to Rhizopus delemar
por: Choudhury, Quanita J., et al.
Publicado: (2022)

Pathways of Pathogenicity: Transcriptional Stages of Germination in the Fatal Fungal Pathogen Rhizopus delemar
por: Sephton-Clark, Poppy C. S., et al.
Publicado: (2018)

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis
por: Alkhazraji, Sondus, et al.
Publicado: (2020)

Novel Secreted Peptides From Rhizopus arrhizus var. delemar With Immunomodulatory Effects That Enhance Fungal Pathogenesis
por: Soliman, Sameh S. M., et al.
Publicado: (2022)

Comparative genome-wide analysis of extracellular small RNAs from the mucormycosis pathogen Rhizopus delemar
por: Liu, Muxing, et al.
Publicado: (2018)

Comparative proteomics of Rhizopus delemar ATCC 20344 unravels the role of amino acid catabolism in fumarate accumulation
por: Odoni, Dorett I., et al.
Publicado: (2017)

An evolutionarily diverged mitochondrial protein controls biofilm growth and virulence in Candida albicans
por: Mamouei, Zeinab, et al.
Publicado: (2021)

Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus
por: Gebremariam, Teclegiorgis, et al.
Publicado: (2020)

Utilization of horticultural waste (Apple Pomace) for multiple carbohydrase production from Rhizopus delemar F(2) under solid state fermentation
por: Pathania, Shruti, et al.
Publicado: (2018)

A case report of brainstem hemorrhage due to Rhizopus delemar-induced encephalitis diagnosed by metagenomic next-generation sequencing (mNGS)
por: Xie, Shuhua, et al.
Publicado: (2023)

Galactomannan Is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis
por: Gebremariam, Teclegiorgis, et al.
Publicado: (2019)

Safety evaluation of the food enzyme glucan‐1,4‐α‐glucosidase from the non‐genetically modified Rhizopus delemar strain CU634‐1775
por: Lambré, Claude, et al.
Publicado: (2023)

Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine
por: Liu, Mingfu, et al.
Publicado: (2015)

119. A Humanized Antibody Targeting the CotH Invasins is Protective Against Murine Mucormycosis
por: Gu, Yiyou, et al.
Publicado: (2021)

Transformation and CRISPR-Cas9-mediated homologous recombination in the fungus Rhizopus microsporus
por: Lax, Carlos, et al.
Publicado: (2022)

2393. Evaluation of Antifungal Treatment in a Neutropenic Mouse Model of Scedosporiosis
por: Alkhazraji, Sondus, et al.
Publicado: (2018)

Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens
por: Mamouei, Zeinab, et al.
Publicado: (2018)

APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis
por: Gebremariam, Teclegiorgis, et al.
Publicado: (2019)

Development of a plasmid free CRISPR-Cas9 system for the genetic modification of Mucor circinelloides
por: Nagy, Gábor, et al.
Publicado: (2017)

Piéces de clavecin (1724) Nouvelles suites de piéces de clavecin (1728) /
por: Rameau, Jean Philippe, 1683-1764
Publicado: (1999)

Révoltes des Indiens Tarahumars (1626-1724) Joseph Neumann
por: Neumann, Joseph, 1648-1732
Publicado: (1969)

A bacterial endosymbiont of the fungus Rhizopus microsporus drives phagocyte evasion and opportunistic virulence
por: Itabangi, Herbert, et al.
Publicado: (2022)

1724. Murine Efficacy Studies of Sulopenem Against Bacillus anthracis
por: Puttagunta, Sailaja, et al.
Publicado: (2022)

The unique reconstructed 1724 Cahman organ in the Kristine Church, Falun, Sweden
Publicado: (1983)

Amendment to the Draft Minutes of Committee of Council (CERN/CC/1724/Draft)
Publicado: (1988)

Programmable plasmid interference by the CRISPR-Cas system in Thermococcus kodakarensis
por: Elmore, Joshua R., et al.
Publicado: (2013)

CRISPR-Cas System in Antibiotic Resistance Plasmids in Klebsiella pneumoniae
por: Kamruzzaman, Muhammad, et al.
Publicado: (2020)

The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection
por: Singh, Shakti, et al.
Publicado: (2019)

Development of an in vivo cleavable donor plasmid for targeted transgene integration by CRISPR-Cas9 and CRISPR-Cas12a
por: Ishibashi, Riki, et al.
Publicado: (2022)

GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis
por: Alqarihi, Abdullah, et al.
Publicado: (2020)

Book Review: Nieuw licht op Hendrik van Deventer (1651–1724)
por: Schweikardt, Christoph
Publicado: (2004)

Concerts pour la flûte traversière avec la basse chiffrée, 1724 /
por: Montéclair, Michel Pignolet de, 1667-1737
Publicado: (2003)

Corrigendum to Document "Draft Minutes of the Committee of Council CERN/CC/1724/Draft"
Publicado: (1988)

Niclosamide-loaded nanoparticles disrupt Candida biofilms and protect mice from mucosal candidiasis
por: Sutar, Yogesh, et al.
Publicado: (2022)

Efficient CRISPR/Cas9 Plasmids for Rapid and Versatile Genome Editing in Drosophila
por: Gokcezade, Joseph, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7ba60gioeq2ttcguleit23i5kk