973. Single-cell RNA Sequencing Analysis of Zika Virus Infection in Human Stem Cell-Derived Cerebral Organoids

BACKGROUND: The molecular mechanisms underpinning the neurologic and congenital pathologies caused by Zika virus (ZIKV) infection remain poorly understood. One barrier has been the lack of relevant model systems for the developing human brain; however, thanks to advances in the stem cell field, we c...

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Detalles Bibliográficos
Autores principales: Ocwieja, Karen, Stanton, Alexandra, Richards, Alexsia, Antonucci, Jenna, Hughes, Travis, Shalek, Alex, Jaenisch, Rudolph, Gehrke, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
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Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808757/
http://dx.doi.org/10.1093/ofid/ofz359.075

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