1545. Development of a Linear Mixed-Effect Pharmacodynamic Model to Quantify the Effects of Frequently Prescribed Antimicrobials on QT Interval Prolongation in Hospitalized Patients

BACKGROUND: Torsades de pointes is a life-threatening ventricular tachycardia associated with prolongation of the QT interval. Many diseases and medications have been implicated as potentially prolonging the QT interval, but little data exists regarding the means of quantifying this risk. The aim of...

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Detalles Bibliográficos
Autores principales: Farkas, Andras, Woods, Krystina L, Ciummo, Francesco, Shah, Ami, Sassine, Joseph, Olivo Freites, Christian, Daroczi, Gergely, Yassin, Arsheena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808832/
http://dx.doi.org/10.1093/ofid/ofz360.1409

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