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971. The Role of Inflammation and Innate Effectors in Passive Immunization for Acinetobacter baumannii Infections
BACKGROUND: We have previously demonstrated that A. baumannii virulence is driven by avoidance of innate effector clearance, resulting in LPS-TLR4 triggering of excess inflammation in the host. We also raised a monoclonal antibody (MAb) that improved survival of mice lethally infected with A. bauman...
Autores principales: | Nielsen, Travis B, Yan, Jun, Luna, Brian M, Talyansky, Yuli, Bonomo, Robert A, Spellberg, Brad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808996/ http://dx.doi.org/10.1093/ofid/ofz359.073 |
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