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1829. The Paradox of KPC Bearing Strains of Klebsiella pneumoniae with the D179Y Substitution: Resistance to Ceftazidine/Avibactam (CZA) and Susceptibility to Meropenem (MEM)

BACKGROUND: Resistance to CZA is a serious limitation of treatment for KPC bearing Enterobacteriaceae infections. Recently, a single amino acid substitution (D179Y) was described in KPC-2 and KPC-3 bearing CZA-resistant K. pneumoniae recovered from patients failing treatment. In class A β-lactamases...

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Detalles Bibliográficos
Autores principales:	Barnes, Melissa D, Taracilla, Magdalena A, Rutter, Joseph D, Nguyen, Minh-Hong, Shields, Ryan K, Clancy, Cornelius J, Bonomo, Robert A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809065/ http://dx.doi.org/10.1093/ofid/ofz359.091

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