1503. Engraftment of Investigational Microbiome Drug, SER-262, in Subjects Receiving Vancomycin Is Associated with Reduced Rates of Recurrence after Primary Clostridium Difficile Infection (CDI)

BACKGROUND: CDI is a 2-hit process requiring C. difficile spores and antibiotic-mediated dysbiosis, a low diversity state of the gut microbiome. Recurrent CDI (rCDI) is common and may be related to inadequate antibiotic concentrations (e.g., metronidazole; MET) or persistent dysbiosis (e.g., vancomy...

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Detalles Bibliográficos
Autores principales: Ford, Christopher, Litcofsky, Kevin, McGovern, Barbara, Pardi, Darrell, Nathan, Richard, Hansen, Val, Brennan, Robert, Pullman, John, Bernardo, Patricia, Tomlinson, Amelia, Horgan, Kevin, Bryant, Jessica, Walsh, Emily, Rodriguez, Michelle, Rogalin, Henry, Wang, Elaine, Henn, Matt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809198/
http://dx.doi.org/10.1093/ofid/ofz360.1367

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