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902. A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of a Single Immunization of Ad26.RSV.preF against RSV Infection in a Viral Challenge Model in Healthy Adults
BACKGROUND: Despite the high disease burden of RSV in older adults and children, there is currently no approved vaccine. Ad26.RSV.preF, an experimental RSV vaccine, has demonstrated immunogenicity and tolerability in first-in-human clinical studies. The aim of this study was to assess the potential...
Autores principales: | DeVincenzo, John, Gymnopoulou, Efi, De Paepe, Els, Murray, Bryan, Rosemary Bastian, Arangassery, Haazen, Wouter, Noulin, Nicolas, Comeaux, Christy, Heijnen, Esther, Eze, Kinglsey, Gilbert, Anthony, Lambkin-Williams, Rob, Schuitemaker, Hanneke, Callendret, Benoit, Sadoff, Jerald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809212/ http://dx.doi.org/10.1093/ofid/ofz359.061 |
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