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1599. AUC24 Vancomycin Bayesian-Based Dosing: Increasing Therapeutic Target Attainment with Decreased TDM Cost

BACKGROUND: Vancomycin efficacy is optimally predicted by the area under the concentration–time profile (AUC24), however, traditional AUC24-based dosing methods involve analytic PK calculations that require both peak and trough drug levels, increasing cost and time compared with trough-based dosing....

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Detalles Bibliográficos
Autores principales: Sabourenkov, Paul E, McLeay, Robert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809216/
http://dx.doi.org/10.1093/ofid/ofz360.1463