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1726. Candida albicans Virulence Genes Induced During Intra-abdominal Candidiasis (IAC) in the Absence of Antifungal Exposure Mediate Echinocandin Resistance

BACKGROUND: We developed and validated a mouse model of C. albicans IAC that mimics peritonitis and abscesses (IAA) in humans, and that is amenable to temporal–spatial transcriptional profiling and virulence studies. METHODS: We measured C. albicans SC5314 gene expression by RNA-Seq (RiboPure extrac...

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Detalles Bibliográficos
Autores principales:	Clancy, Cornelius J, Samanta, Palash, Cheng, Shaoji, Squires, Kevin, Nguyen, Minh-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809290/ http://dx.doi.org/10.1093/ofid/ofz360.1589

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