Electron transport chain biogenesis activated by a JNK-insulin-Myc relay primes mitochondrial inheritance in Drosophila

Oogenesis features an enormous increase in mitochondrial mass and mtDNA copy number, which are required to furnish mature eggs with an adequate supply of mitochondria and to curb the transmission of deleterious mtDNA variants. Quiescent in dividing germ cells, mtDNA replication initiates upon oocyte...

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Detalles Bibliográficos
Autores principales: Wang, Zong-Heng, Liu, Yi, Chaitankar, Vijender, Pirooznia, Mehdi, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809605/
https://www.ncbi.nlm.nih.gov/pubmed/31612862
http://dx.doi.org/10.7554/eLife.49309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809605/
https://www.ncbi.nlm.nih.gov/pubmed/31612862
http://dx.doi.org/10.7554/eLife.49309

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