389. Risk Factors and Outcomes of Patients with Infectious Complications After Surgical Treatment of Blount Disease

BACKGROUND: Blount disease (idiopathic tibia vara) is an uncommon pediatric growth disorder characterized by unequal endochondral ossification of the medial aspect of the proximal tibial growth plate. Management of Blount’s disease involves performing osteotomy for improved outcomes. The objective of the study was to assess risk factors for infection, microbiology, and outcomes in patients following surgical correction. METHODS: This study is a retrospective case–control study of patients who underwent surgery for Blount disease at Children’s Hospital of Michigan, Detroit from January 1, 2000 to January 31, 2019. Charts from 44 patients who underwent surgical correction were reviewed (22 cases and 22 control patients) and analyzed for basic demographics, surgical risk factors, microbiology, treatment durations, and outcomes. RESULTS: A total of 44 patients (22 cases and 22 controls) were included. Baseline characteristics, risk factors, and outcomes are shown in Table 1. Significant risk factors for infection included increased obesity and BMI (P < 0.05). The median time to infection from index surgery was 12.5 days, with 11 (52.4%) of the infections categorized as superficial and 10 (46.6) as deep or organ space. 7 (31.8%) infections were polymicrobial and the common pathogen was Staphylococcus aureus (n = 7, 31.8%) (Table 2). Infected patients had an average of 3.25 incision and drainage procedures, and the average duration of antibiotic therapy was 23 days. CONCLUSION: Obesity with an increased BMI was associated with increased risk of infectious complication following the surgical treatment of Blount’s Disease with Staphylococcus aureus, is the most common pathogen. [Image: see text] [Image: see text] DISCLOSURES: All authors: No reported disclosures.