Cargando…

1617. Mumps in Detention Facilities that House Detained Migrants—United States, September 2018–April 2019

BACKGROUND: Starting in September 2018, an unusually high number of mumps cases were reported in US adult detention facilities. Detention facilities usually involve close contact among detainees, facilitating transmission of mumps. Detainees in close contact with a mumps patient are at increased ris...

Descripción completa

Detalles Bibliográficos
Autores principales: Leung, Jessica, Elson, Diana, Cloud, Brandy, (Cody) McMurray, Dakota, McNall, Rebecca J, Hickman, Carole J, Marlow, Mariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810009/
http://dx.doi.org/10.1093/ofid/ofz360.1481
_version_ 1783462141760634880
author Leung, Jessica
Elson, Diana
Cloud, Brandy
(Cody) McMurray, Dakota
McNall, Rebecca J
Hickman, Carole J
Marlow, Mariel
author_facet Leung, Jessica
Elson, Diana
Cloud, Brandy
(Cody) McMurray, Dakota
McNall, Rebecca J
Hickman, Carole J
Marlow, Mariel
author_sort Leung, Jessica
collection PubMed
description BACKGROUND: Starting in September 2018, an unusually high number of mumps cases were reported in US adult detention facilities. Detention facilities usually involve close contact among detainees, facilitating transmission of mumps. Detainees in close contact with a mumps patient are at increased risk for acquiring mumps and should be offered a dose of MMR vaccine. We summarize the epidemiologic, clinical, and laboratory data for mumps cases in adult detention facilities during September 2018-April 2019. METHODS: Data were collected by health departments and US Immigration and Customs Enforcement (ICE) Health Services Corps and reported to CDC. Cases were classified according to the CSTE case definition for mumps and confirmed by RT-qPCR; molecular sequencing was performed on mumps-positive specimens. RESULTS: From September 2018-April 2019, 389 confirmed and probable mumps cases in adult migrants detained by ICE in 44 detention facilities were reported in 16 states (figure). The median age of patients was 24 years (range: 18–66); 94% were male. Vaccination status was unknown for all patients. Most (80%) patients were exposed while in custody of ICE or other US legal agency, 7% were exposed before apprehension, and custody status at exposure was unknown for 13%. Among 265 patients with data on complications, 15% had orchitis; at least 3 were hospitalized. Mumps genotype G, the most common genotype in US, was identified in specimens from 70 patients. This mumps response included >7,000 MMR vaccine doses distributed to affected facilities, and hundreds of exposed detainees placed under restricted movement in their facility each week. The response is ongoing as new cases continue to be reported. CONCLUSION: This is the first report of mumps outbreaks occurring in multiple states and detention facilities during the same period. These outbreaks are costly and challenging to control. Identifying target groups for vaccination is challenging since detainees are frequently transferred and MMR vaccine does not prevent mumps in persons already exposed and infected. Effective public health interventions require an understanding of detention settings. Development of national guidance and resources for public health response to mumps and other infectious diseases in detention facilities would be beneficial. [Image: see text] DISCLOSURES: All authors: No reported disclosures.
format Online
Article
Text
id pubmed-6810009
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-68100092019-10-28 1617. Mumps in Detention Facilities that House Detained Migrants—United States, September 2018–April 2019 Leung, Jessica Elson, Diana Cloud, Brandy (Cody) McMurray, Dakota McNall, Rebecca J Hickman, Carole J Marlow, Mariel Open Forum Infect Dis Abstracts BACKGROUND: Starting in September 2018, an unusually high number of mumps cases were reported in US adult detention facilities. Detention facilities usually involve close contact among detainees, facilitating transmission of mumps. Detainees in close contact with a mumps patient are at increased risk for acquiring mumps and should be offered a dose of MMR vaccine. We summarize the epidemiologic, clinical, and laboratory data for mumps cases in adult detention facilities during September 2018-April 2019. METHODS: Data were collected by health departments and US Immigration and Customs Enforcement (ICE) Health Services Corps and reported to CDC. Cases were classified according to the CSTE case definition for mumps and confirmed by RT-qPCR; molecular sequencing was performed on mumps-positive specimens. RESULTS: From September 2018-April 2019, 389 confirmed and probable mumps cases in adult migrants detained by ICE in 44 detention facilities were reported in 16 states (figure). The median age of patients was 24 years (range: 18–66); 94% were male. Vaccination status was unknown for all patients. Most (80%) patients were exposed while in custody of ICE or other US legal agency, 7% were exposed before apprehension, and custody status at exposure was unknown for 13%. Among 265 patients with data on complications, 15% had orchitis; at least 3 were hospitalized. Mumps genotype G, the most common genotype in US, was identified in specimens from 70 patients. This mumps response included >7,000 MMR vaccine doses distributed to affected facilities, and hundreds of exposed detainees placed under restricted movement in their facility each week. The response is ongoing as new cases continue to be reported. CONCLUSION: This is the first report of mumps outbreaks occurring in multiple states and detention facilities during the same period. These outbreaks are costly and challenging to control. Identifying target groups for vaccination is challenging since detainees are frequently transferred and MMR vaccine does not prevent mumps in persons already exposed and infected. Effective public health interventions require an understanding of detention settings. Development of national guidance and resources for public health response to mumps and other infectious diseases in detention facilities would be beneficial. [Image: see text] DISCLOSURES: All authors: No reported disclosures. Oxford University Press 2019-10-23 /pmc/articles/PMC6810009/ http://dx.doi.org/10.1093/ofid/ofz360.1481 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Abstracts
Leung, Jessica
Elson, Diana
Cloud, Brandy
(Cody) McMurray, Dakota
McNall, Rebecca J
Hickman, Carole J
Marlow, Mariel
1617. Mumps in Detention Facilities that House Detained Migrants—United States, September 2018–April 2019
title 1617. Mumps in Detention Facilities that House Detained Migrants—United States, September 2018–April 2019
title_full 1617. Mumps in Detention Facilities that House Detained Migrants—United States, September 2018–April 2019
title_fullStr 1617. Mumps in Detention Facilities that House Detained Migrants—United States, September 2018–April 2019
title_full_unstemmed 1617. Mumps in Detention Facilities that House Detained Migrants—United States, September 2018–April 2019
title_short 1617. Mumps in Detention Facilities that House Detained Migrants—United States, September 2018–April 2019
title_sort 1617. mumps in detention facilities that house detained migrants—united states, september 2018–april 2019
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810009/
http://dx.doi.org/10.1093/ofid/ofz360.1481
work_keys_str_mv AT leungjessica 1617mumpsindetentionfacilitiesthathousedetainedmigrantsunitedstatesseptember2018april2019
AT elsondiana 1617mumpsindetentionfacilitiesthathousedetainedmigrantsunitedstatesseptember2018april2019
AT cloudbrandy 1617mumpsindetentionfacilitiesthathousedetainedmigrantsunitedstatesseptember2018april2019
AT codymcmurraydakota 1617mumpsindetentionfacilitiesthathousedetainedmigrantsunitedstatesseptember2018april2019
AT mcnallrebeccaj 1617mumpsindetentionfacilitiesthathousedetainedmigrantsunitedstatesseptember2018april2019
AT hickmancarolej 1617mumpsindetentionfacilitiesthathousedetainedmigrantsunitedstatesseptember2018april2019
AT marlowmariel 1617mumpsindetentionfacilitiesthathousedetainedmigrantsunitedstatesseptember2018april2019