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LB6. EDP-938, a Novel RSV N-Inhibitor, Administered Once or Twice Daily Was Safe and Demonstrated Robust Antiviral and Clinical Efficacy in a Healthy Volunteer Challenge Study
BACKGROUND: Respiratory syncytial virus (RSV) represents an important global health challenge with significant morbidity and mortality in infants, elderly, and immunocompromised adults. No effective therapy is currently available. EDP-938 demonstrates potent in vitro activity against RSV Subtypes A...
Autores principales: | Coakley, Eoin, Ahmad, Alaa, Larson, Kajal, McClure, Ty, Lin, Kai, Tenhoor, Kursten, Eze, Kingsley, Noulin, Nicolas, Horvathova, Veronika, Murray, Bryan, Baillet, Mark, Mori, Julie, Adda, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810094/ http://dx.doi.org/10.1093/ofid/ofz415.2489 |
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