Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis

A patient with multiple sclerosis presented with seronegative C. burnetii endocarditis diagnosed using C. burnetii–specific polymerase chain reaction and fluorescence in situ hybridization on cardiovascular biopsy. This case supports the necessity of a systematic polymerase chain reaction testing of...

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Autores principales: Melenotte, Cléa, Loukil, Ahmed, Rico, Audrey, Lepidi, Hubert, Raoult, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810175/
https://www.ncbi.nlm.nih.gov/pubmed/31660380
http://dx.doi.org/10.1093/ofid/ofz429
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author Melenotte, Cléa
Loukil, Ahmed
Rico, Audrey
Lepidi, Hubert
Raoult, Didier
author_facet Melenotte, Cléa
Loukil, Ahmed
Rico, Audrey
Lepidi, Hubert
Raoult, Didier
author_sort Melenotte, Cléa
collection PubMed
description A patient with multiple sclerosis presented with seronegative C. burnetii endocarditis diagnosed using C. burnetii–specific polymerase chain reaction and fluorescence in situ hybridization on cardiovascular biopsy. This case supports the necessity of a systematic polymerase chain reaction testing of removed cardiac valves because blood culture–negative endocarditis can be pauci-symptomatic, and serological tests can be negative in cases of immunosuppression.
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spelling pubmed-68101752019-10-28 Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis Melenotte, Cléa Loukil, Ahmed Rico, Audrey Lepidi, Hubert Raoult, Didier Open Forum Infect Dis Brief Report A patient with multiple sclerosis presented with seronegative C. burnetii endocarditis diagnosed using C. burnetii–specific polymerase chain reaction and fluorescence in situ hybridization on cardiovascular biopsy. This case supports the necessity of a systematic polymerase chain reaction testing of removed cardiac valves because blood culture–negative endocarditis can be pauci-symptomatic, and serological tests can be negative in cases of immunosuppression. Oxford University Press 2019-10-04 /pmc/articles/PMC6810175/ /pubmed/31660380 http://dx.doi.org/10.1093/ofid/ofz429 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Melenotte, Cléa
Loukil, Ahmed
Rico, Audrey
Lepidi, Hubert
Raoult, Didier
Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis
title Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis
title_full Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis
title_fullStr Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis
title_full_unstemmed Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis
title_short Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis
title_sort blood culture–negative cardiovascular infection in a patient with multiple sclerosis
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810175/
https://www.ncbi.nlm.nih.gov/pubmed/31660380
http://dx.doi.org/10.1093/ofid/ofz429
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AT lepidihubert bloodculturenegativecardiovascularinfectioninapatientwithmultiplesclerosis
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