Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans

Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans. Diphtheria toxin diversification could decrease effectiveness of diphtheria toxoid vaccine and diphtheria antitoxin f...

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Autores principales: Otsuji, Ken, Fukuda, Kazumasa, Ogawa, Midori, Saito, Mitsumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810190/
https://www.ncbi.nlm.nih.gov/pubmed/31625851
http://dx.doi.org/10.3201/eid2511.181455
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author Otsuji, Ken
Fukuda, Kazumasa
Ogawa, Midori
Saito, Mitsumasa
author_facet Otsuji, Ken
Fukuda, Kazumasa
Ogawa, Midori
Saito, Mitsumasa
author_sort Otsuji, Ken
collection PubMed
description Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans. Diphtheria toxin diversification could decrease effectiveness of diphtheria toxoid vaccine and diphtheria antitoxin for preventing and treating illnesses caused by this bacterium.
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spelling pubmed-68101902019-11-01 Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans Otsuji, Ken Fukuda, Kazumasa Ogawa, Midori Saito, Mitsumasa Emerg Infect Dis Research Letter Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans. Diphtheria toxin diversification could decrease effectiveness of diphtheria toxoid vaccine and diphtheria antitoxin for preventing and treating illnesses caused by this bacterium. Centers for Disease Control and Prevention 2019-11 /pmc/articles/PMC6810190/ /pubmed/31625851 http://dx.doi.org/10.3201/eid2511.181455 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Otsuji, Ken
Fukuda, Kazumasa
Ogawa, Midori
Saito, Mitsumasa
Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans
title Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans
title_full Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans
title_fullStr Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans
title_full_unstemmed Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans
title_short Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans
title_sort mutation and diversity of diphtheria toxin in corynebacterium ulcerans
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810190/
https://www.ncbi.nlm.nih.gov/pubmed/31625851
http://dx.doi.org/10.3201/eid2511.181455
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