Non-Leishmania Parasite in Fatal Visceral Leishmaniasis–Like Disease, Brazil

Through whole-genome sequencing analysis, we identified non-Leishmania parasites isolated from a man with a fatal visceral leishmaniasis–like illness in Brazil. The parasites infected mice and reproduced the patient’s clinical manifestations. Molecular epidemiologic studies are needed to ascertain w...

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Detalles Bibliográficos
Autores principales: Maruyama, Sandra R., de Santana, Alynne K.M., Takamiya, Nayore T., Takahashi, Talita Y., Rogerio, Luana A., Oliveira, Caio A.B., Milanezi, Cristiane M., Trombela, Viviane A., Cruz, Angela K., Jesus, Amélia R., Barreto, Aline S., da Silva, Angela M., Almeida, Roque P., Ribeiro, José M., Silva, João S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810192/
https://www.ncbi.nlm.nih.gov/pubmed/31625841
http://dx.doi.org/10.3201/eid2511.181548
Descripción
Sumario:Through whole-genome sequencing analysis, we identified non-Leishmania parasites isolated from a man with a fatal visceral leishmaniasis–like illness in Brazil. The parasites infected mice and reproduced the patient’s clinical manifestations. Molecular epidemiologic studies are needed to ascertain whether a new infectious disease is emerging that can be confused with leishmaniasis.

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