Cargando…
Zika virus degrades the ω-3 fatty acid transporter Mfsd2a in brain microvascular endothelial cells and impairs lipid homeostasis
Zika virus (ZIKV) infection during pregnancy increases the risk of postnatal microcephaly. Neurovascular function provides a homeostatic environment for proper brain development. The major facilitator superfamily domain-containing protein 2 (Mfsd2a) is selectively expressed in human brain microvascu...
Autores principales: | Zhou, Jia, Chi, Xiaojing, Cheng, Min, Huang, Xingyao, Liu, Xiuying, Fan, Jingjing, Xu, Hua, Lin, Tianli, Shi, Lei, Qin, Chengfeng, Yang, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810275/ https://www.ncbi.nlm.nih.gov/pubmed/31681849 http://dx.doi.org/10.1126/sciadv.aax7142 |
Ejemplares similares
-
The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis
por: Wong, Bernice H., et al.
Publicado: (2022) -
The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis
por: Perland, Emelie, et al.
Publicado: (2016) -
MFSD12 affects glycosphingolipid metabolism by modulating lysosome homeostasis
por: Hong, Yun, et al.
Publicado: (2022) -
Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability
por: Lekholm, Emilia, et al.
Publicado: (2017) -
The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP
por: Massa López, David, et al.
Publicado: (2019)