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306. CD8+ T-Cell Responses to Chronic Hepatitis C in Pregnancy

BACKGROUND: Chronic hepatitis C virus (HCV) infection is marked by stable, high -level viremia and a failed T-cell response. HCV-specific CD4+ helper T cells are rare, and CD8+ cytotoxic T cells are functionally exhausted or ineffective due to viral escape mutations. Postpartum, a subset of infected...

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Detalles Bibliográficos
Autores principales: Brooks, Stephanie, Coss, Samantha, Walker, Christopher, Honegger, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810316/
http://dx.doi.org/10.1093/ofid/ofz360.379

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