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2226. Impact of Prior and Concomitant Antibacterial Therapy on Outcomes in the ASPECT-NP Randomized, Controlled Trial of Ceftolozane/Tazobactam (C/T) vs. Meropenem (MEM) in Patients with Ventilated Nosocomial Pneumonia (NP)
BACKGROUND: NP is a frequent healthcare-acquired infection associated with high mortality; rising resistance rates among causative Gram-negative pathogens require new treatment options. In the randomized, controlled, double-blind, phase 3 ASPECT-NP trial, C/T (at double the initially approved dose)...
Autores principales: | Wunderink, Richard G, Bruno, Christopher, Martin-Loeches, Ignacio, Kollef, Marin, Timsit, Jean-Francois, Yu, Brian, Huntington, Jennifer A, Li, Linping, Jensen, Erin, Wolf, Dominik, Butterton, Joan R, Rhee, Elizabeth G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810350/ http://dx.doi.org/10.1093/ofid/ofz360.1904 |
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