Cargando…
2601. Identification of Staphylococcus aureus Genetic Factors Associatiated with the Subversion of Macrophage Phagosomal Acidification
BACKGROUND: S. aureus is a major medical pathogen contributing to healthcare-associated costs and mortality. Metastatic S. aureus infection is commonly associated with skin and soft-tissue infections. Macrophages as resident tissue phagocytes are essential for bacterial clearance and effectively pha...
Autores principales: | Morris, Paul E R, Renshaw, Stephen, Foster, Simon J, Peden, Andrew, Dockrell, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810580/ http://dx.doi.org/10.1093/ofid/ofz360.2279 |
Ejemplares similares
-
Sottsass associati
Publicado: (1988) -
Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages
por: Jubrail, Jamil, et al.
Publicado: (2015) -
The Role of Macrophages in Staphylococcus aureus Infection
por: Pidwill, Grace R., et al.
Publicado: (2021) -
Salmonella Typhimurium impairs glycolysis-mediated acidification of phagosomes to evade macrophage defense
por: Gutiérrez, Saray, et al.
Publicado: (2021) -
TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria
por: Breyer, Felix, et al.
Publicado: (2021)