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494. Fitness Cost of mcr-1-Mediated Colistin Resistance in Carbapenemase-Producing Klebsiella pneumoniae

BACKGROUND: The emergence of mobile colistin resistance gene mcr-1, a plasmid-borne polymyxin resistance mechanism, in carbapenem-resistant Klebsiella pneumoniae is an alarming concern. However, previous studies showed that the acquisition of mcr-1 was associated with a significant biological fitnes...

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Detalles Bibliográficos
Autores principales:	Lin, Yi-Tsung, Cheng, Yi-Hsiang, Chou, Sheng-Hua, Huang, Ying-Chi, Chen, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810815/ http://dx.doi.org/10.1093/ofid/ofz360.563

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