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674. Pre-Clinical and Phase I Safety Data for Anti-Pseudomonas aeruginosa Human Monoclonal Antibody AR-105

BACKGROUND: Anti-bacterial monoclonal antibodies can serve as a new treatment modality for difficult to treat infections. AR-105 is a fully human IgG1 monoclonal antibody (mAb) that binds to an extracellular polysaccharide epitope of Pseudomonas aeruginosa (PA) and was shown to mediate in vitro comp...

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Detalles Bibliográficos
Autores principales: Loos, Andreas, Weich, Nadine, Woo, Jennifer, Lalonde, Guy, Yee, Luisa, Dummer, Wolfgang, Truong, Vu L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811070/
http://dx.doi.org/10.1093/ofid/ofz360.742