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715. Bulgecin A lowers Imipenem MICs in Clinical MDR Acinetobacter baumannii (ACB) Strains

BACKGROUND: Genetic screening of ACB has revealed genes that confer increased susceptibility to β-lactams when these genes are disrupted suggesting novel drug targets. One such target is lytic transglycosylase, LT. Bulgecin A (BlgA) is a natural product of Paraburkholderia acidophila and an LT inhib...

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Detalles Bibliográficos
Autores principales:	Skalweit, Marion J, Rojas, Laura J, Bonomo, Robert A, Dik, David A, Tomoshige, Shusuke, Mobashery, Shahriar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811142/ http://dx.doi.org/10.1093/ofid/ofz360.783

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