737. Novel Glycans Reduce Carbapenem-Resistant Enterobacteriaceae and Vancomycin-Resistant Enterococci Colonization in an Ex Vivo Assay by Supporting Growth and Diversity of Commensal Microbiota at the Expense of MultiDrug-Resistant Organisms (MDRO)

BACKGROUND: Infections with Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococci (VRE) can result in a 50% mortality rate in compromised hosts. A major risk factor for clinical infection is intestinal colonization with CRE or VRE. There are currently no FDA-approved com...

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Detalles Bibliográficos
Autores principales: LeBlanc, Gabby, Brooks, Brandon, Hartman, Madeline, Hecht, Maxwell B, Luong, Hoa, Pan, Zheng, Sofen, Stephen, Miller, Kelsey J, Meehan, Brian, Mahowald, Michael A, Yatsunenko, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811179/
http://dx.doi.org/10.1093/ofid/ofz360.805

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