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635. Genomic Evolution and Progression of Antimicrobial Resistance in a Series of Extensively Drug-Resistant Pseudomonas aeruginosa (XDR-Pa) Isolates from a Cystic Fibrosis Lung Transplant Recipient
BACKGROUND: Chronic respiratory infection due to extensively drug-resistant Pseudomonas aeruginosa (XDR-Pa) is a significant cause of mortality in cystic fibrosis (CF) patients. The CF respiratory anatomy, chronic antibiotic use, and PA colonization creates a milieu for high evolutionary pressure an...
Autores principales: | Yasmin, Mohamad, Adams, Mark D, Marshall, Steven, Abbo, Lilian, Benjamino, Jacquelynn, Krishnan, Nikhil, Rojas, Laura J, Scott, Jacob, Jacobs, Michael, Rhoads, Daniel D, Perez-Cardona, Armando, Martinez, Octavio, Perez, Federico, Bonomo, Robert A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811252/ http://dx.doi.org/10.1093/ofid/ofz360.703 |
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