Cargando…

Trichophyton rubrum Azole Resistance Mediated by a New ABC Transporter, TruMDR3

The mechanisms of terbinafine resistance in a set of clinical isolates of Trichophyton rubrum have been studied recently. Of these isolates, TIMM20092 also showed reduced sensitivity to azoles. The azole resistance of TIMM20092 could be inhibited by milbemycin oxime, prompting us to examine the pote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Monod, Michel, Feuermann, Marc, Salamin, Karine, Fratti, Marina, Makino, Maya, Alshahni, Mohamed Mahdi, Makimura, Koichi, Yamada, Tsuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811443/ https://www.ncbi.nlm.nih.gov/pubmed/31501141 http://dx.doi.org/10.1128/AAC.00863-19

Ejemplares similares

Gene Amplification of CYP51B: a New Mechanism of Resistance to Azole Compounds in Trichophyton indotineae
por: Yamada, Tsuyoshi, et al.
Publicado: (2022)

Two different types of tandem sequences mediate the overexpression of TinCYP51B in azole-resistant Trichophyton indotineae
por: Yamada, Tsuyoshi, et al.
Publicado: (2023)

ERG11 Gene Mutations and MDR1 Upregulation Confer Pan-Azole Resistance in Candida tropicalis Causing Disseminated Candidiasis in an Acute Lymphoblastic Leukemia Patient on Posaconazole Prophylaxis
por: You, Liangshun, et al.
Publicado: (2017)

Azole Resistance Mechanisms in Pathogenic Malassezia furfur
por: Leong, Cheryl, et al.
Publicado: (2021)

Aneuploidy Is Associated with Azole Resistance in Aspergillus fumigatus
por: Khateb, Aiah, et al.
Publicado: (2023)

Azole Resistance of Environmental and Clinical Aspergillus fumigatus Isolates from Switzerland
por: Riat, Arnaud, et al.
Publicado: (2018)

Deletion of cox7c Results in Pan-Azole Resistance in Aspergillus fumigatus
por: Chen, Mingcong, et al.
Publicado: (2022)

Limited ERG11 Mutations Identified in Isolates of Candida auris Directly Contribute to Reduced Azole Susceptibility
por: Healey, Kelley R., et al.
Publicado: (2018)

The Evolution of Azole Resistance in Candida albicans Sterol 14α-Demethylase (CYP51) through Incremental Amino Acid Substitutions
por: Warrilow, Andrew G., et al.
Publicado: (2019)

The Heterodimeric ABC Transporter EfrCD Mediates Multidrug Efflux in Enterococcus faecalis
por: Hürlimann, Lea M., et al.
Publicado: (2016)

The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus
por: Kühbacher, Alexander, et al.
Publicado: (2023)

Secretion of and Self-Resistance to the Novel Fibupeptide Antimicrobial Lugdunin by Distinct ABC Transporters in Staphylococcus lugdunensis
por: Krauss, Sophia, et al.
Publicado: (2020)

A Novel Gene Amplification Causes Upregulation of the PatAB ABC Transporter and Fluoroquinolone Resistance in Streptococcus pneumoniae
por: Baylay, Alison J., et al.
Publicado: (2015)

Inhibitor-Resistant Mutants Give Important Insights into Candida albicans ABC Transporter Cdr1 Substrate Specificity and Help Elucidate Efflux Pump Inhibition
por: Niimi, Masakazu, et al.
Publicado: (2022)

Molecular Characterization of Mycobacterium ulcerans DNA Gyrase and Identification of Mutations Reducing Susceptibility to Quinolones In Vitro
por: Kim, Hyun, et al.
Publicado: (2022)

Cyclic AMP Effectors in African Trypanosomes Revealed by Genome-Scale RNA Interference Library Screening for Resistance to the Phosphodiesterase Inhibitor CpdA
por: Gould, Matthew K., et al.
Publicado: (2013)

Mutagenesis Mapping of the Protein-Protein Interaction Underlying FusB-Type Fusidic Acid Resistance
por: Cox, Georgina, et al.
Publicado: (2013)

The Mu Subunit of Plasmodium falciparum Clathrin-Associated Adaptor Protein 2 Modulates In Vitro Parasite Response to Artemisinin and Quinine
por: Henriques, Gisela, et al.
Publicado: (2015)

Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles
por: Makena, Anne, et al.
Publicado: (2016)

β-Lactamase Characterization of Gram-Negative Pathogens Recovered from Patients Enrolled in the Phase 2 Trials for Ceftazidime-Avibactam: Clinical Efficacies Analyzed against Subsets of Molecularly Characterized Isolates
por: Mendes, Rodrigo E., et al.
Publicado: (2016)

Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates
por: Karah, Nabil, et al.
Publicado: (2016)

First Report of cfr-Carrying Plasmids in the Pandemic Sequence Type 22 Methicillin-Resistant Staphylococcus aureus Staphylococcal Cassette Chromosome mec Type IV Clone
por: Shore, Anna C., et al.
Publicado: (2016)

Identification of EnvC and Its Cognate Amidases as Novel Determinants of Intrinsic Resistance to Cationic Antimicrobial Peptides
por: Oguri, Tamiko, et al.
Publicado: (2016)

Rapid Emergence and Evolution of Staphylococcus aureus Clones Harboring fusC-Containing Staphylococcal Cassette Chromosome Elements
por: Baines, Sarah L., et al.
Publicado: (2016)

Potential of Tetracycline Resistance Proteins To Evolve Tigecycline Resistance
por: Linkevicius, Marius, et al.
Publicado: (2016)

The MSPDBL2 Codon 591 Polymorphism Is Associated with Lumefantrine In Vitro Drug Responses in Plasmodium falciparum Isolates from Kilifi, Kenya
por: Ochola-Oyier, Lynette Isabella, et al.
Publicado: (2015)

Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae at a Single Institution: Insights into Endemicity from Whole-Genome Sequencing
por: Mathers, Amy J., et al.
Publicado: (2015)

Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies
por: Walker, Louise A., et al.
Publicado: (2015)

Expression of Plasmodium vivax crt-o Is Related to Parasite Stage but Not Ex Vivo Chloroquine Susceptibility
por: Pava, Zuleima, et al.
Publicado: (2015)

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers
por: Brem, Jürgen, et al.
Publicado: (2015)

Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A β-Lactamase with a Monobactam Substrate
por: Vandavasi, Venu Gopal, et al.
Publicado: (2016)

Missense Mutations in the Unfoldase ClpC1 of the Caseinolytic Protease Complex Are Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis
por: Yee, Michelle, et al.
Publicado: (2017)

Echinocandin Resistance in Candida Species Isolates from Liver Transplant Recipients
por: Prigent, Gwénolé, et al.
Publicado: (2017)

In Vitro Tolerance of Drug-Naive Staphylococcus aureus Strain FDA209P to Vancomycin
por: Singh, Madhuri, et al.
Publicado: (2017)

Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin
por: Yu, Xia, et al.
Publicado: (2016)

Homologous Recombination within Large Chromosomal Regions Facilitates Acquisition of β-Lactam and Vancomycin Resistance in Enterococcus faecium
por: García-Solache, Mónica, et al.
Publicado: (2016)

Characterization of In Vitro Resistance Development to the Novel Echinocandin CD101 in Candida Species
por: Locke, Jeffrey B., et al.
Publicado: (2016)

Interaction of Avibactam with Class B Metallo-β-Lactamases
por: Abboud, Martine I., et al.
Publicado: (2016)

IMP-27, a Unique Metallo-β-Lactamase Identified in Geographically Distinct Isolates of Proteus mirabilis
por: Dixon, Nyssa, et al.
Publicado: (2016)

The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling
por: Dzyubak, Ekaterina, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ddbmt6lvshb8fajofghv54gl04