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PD-1 Blockade and TLR7 Activation Lack Therapeutic Benefit in Chronic Simian Immunodeficiency Virus-Infected Macaques on Antiretroviral Therapy

Antiretroviral therapy (ART) limits human immunodeficiency virus 1 (HIV-1) replication but does not eliminate the long-lived reservoir established shortly after viral acquisition. A successful HIV cure intervention necessitates either elimination or generation of long-term immune control of the pers...

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Detalles Bibliográficos
Autores principales: Bekerman, Elena, Hesselgesser, Joseph, Carr, Brian, Nagel, Mark, Hung, Magdeleine, Wang, Adele, Stapleton, Lance, von Gegerfelt, Agneta, Elyard, Hanne Andersen, Lifson, Jeffrey D., Geleziunas, Romas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811450/
https://www.ncbi.nlm.nih.gov/pubmed/31501143
http://dx.doi.org/10.1128/AAC.01163-19