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ASCs-Exosomes Recover Coupling Efficiency and Mitochondrial Membrane Potential in an in vitro Model of ALS

The amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by motoneurons death. Mutations in the superoxide dismutase 1 (SOD1) protein have been identified to be related to the disease. Beyond the different altered pathways, the mitochondrial dysfunction is one of t...

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Detalles Bibliográficos
Autores principales: Calabria, Elisa, Scambi, Ilaria, Bonafede, Roberta, Schiaffino, Lorenzo, Peroni, Daniele, Potrich, Valentina, Capelli, Carlo, Schena, Federico, Mariotti, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811497/
https://www.ncbi.nlm.nih.gov/pubmed/31680811
http://dx.doi.org/10.3389/fnins.2019.01070