Altered dendritic spine function and integration in a mouse model of fragile X syndrome

Cellular and circuit hyperexcitability are core features of fragile X syndrome and related autism spectrum disorder models. However, the cellular and synaptic bases of this hyperexcitability have proved elusive. We report in a mouse model of fragile X syndrome, glutamate uncaging onto individual den...

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Detalles Bibliográficos
Autores principales: Booker, Sam A., Domanski, Aleksander P. F., Dando, Owen R., Jackson, Adam D., Isaac, John T. R., Hardingham, Giles E., Wyllie, David J. A., Kind, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811549/
https://www.ncbi.nlm.nih.gov/pubmed/31645626
http://dx.doi.org/10.1038/s41467-019-11891-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811549/
https://www.ncbi.nlm.nih.gov/pubmed/31645626
http://dx.doi.org/10.1038/s41467-019-11891-6

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