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Dual Optical Signal-based Intraocular Pressure-sensing Principle Using Pressure-sensitive Mechanoluminescent ZnS:Cu/PDMS Soft Composite

This paper presents a novel principle for intraocular pressure (IOP)-sensing (monitoring) based on a pressure-sensitive soft composite in which a dual optical signal is produced in response to impulsive pressure input. For the initial assessment of the new IOP sensing principle, a human eye is model...

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Autores principales: Kim, Yooil, Roy, Sunanda, Jung, Gwang-Yong, Oh, Jung-Sik, Kim, Gi-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811554/
https://www.ncbi.nlm.nih.gov/pubmed/31645632
http://dx.doi.org/10.1038/s41598-019-51771-z
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author Kim, Yooil
Roy, Sunanda
Jung, Gwang-Yong
Oh, Jung-Sik
Kim, Gi-Woo
author_facet Kim, Yooil
Roy, Sunanda
Jung, Gwang-Yong
Oh, Jung-Sik
Kim, Gi-Woo
author_sort Kim, Yooil
collection PubMed
description This paper presents a novel principle for intraocular pressure (IOP)-sensing (monitoring) based on a pressure-sensitive soft composite in which a dual optical signal is produced in response to impulsive pressure input. For the initial assessment of the new IOP sensing principle, a human eye is modeled as the spherically shaped shell structure filled with the pressurized fluid, including cornea, sclera, lens and zonular fiber, and a fluid–structure interaction (FSI) analysis was performed to determine the correlation between the internal pressure and deformation (i.e., strain) rate of the spherical shell structure filled with fluid by formulating the finite element model. The FSI analysis results for human eye model are experimentally validated using a proof-of-conceptual experimental model consisting of a pressurized spherical shell structure filled with fluid and a simple air-puff actuation system. In this study, a mechanoluminescent ZnS:Cu- polydimethylsiloxane (PDMS)-based soft composite is fabricated and used to generate the dual optical signal because mechanically driven ZnS:Cu/PDMS soft composite can emit strong luminescence, suitable for soft sensor applications. Similar to the corneal behavior of the human eye, inward and outward deformations occur on the soft composite attached to the spherical shell structure in response to air puffing, resulting in a dual optical signal in the mechnoluminescence (ML) soft composite.
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spelling pubmed-68115542019-10-25 Dual Optical Signal-based Intraocular Pressure-sensing Principle Using Pressure-sensitive Mechanoluminescent ZnS:Cu/PDMS Soft Composite Kim, Yooil Roy, Sunanda Jung, Gwang-Yong Oh, Jung-Sik Kim, Gi-Woo Sci Rep Article This paper presents a novel principle for intraocular pressure (IOP)-sensing (monitoring) based on a pressure-sensitive soft composite in which a dual optical signal is produced in response to impulsive pressure input. For the initial assessment of the new IOP sensing principle, a human eye is modeled as the spherically shaped shell structure filled with the pressurized fluid, including cornea, sclera, lens and zonular fiber, and a fluid–structure interaction (FSI) analysis was performed to determine the correlation between the internal pressure and deformation (i.e., strain) rate of the spherical shell structure filled with fluid by formulating the finite element model. The FSI analysis results for human eye model are experimentally validated using a proof-of-conceptual experimental model consisting of a pressurized spherical shell structure filled with fluid and a simple air-puff actuation system. In this study, a mechanoluminescent ZnS:Cu- polydimethylsiloxane (PDMS)-based soft composite is fabricated and used to generate the dual optical signal because mechanically driven ZnS:Cu/PDMS soft composite can emit strong luminescence, suitable for soft sensor applications. Similar to the corneal behavior of the human eye, inward and outward deformations occur on the soft composite attached to the spherical shell structure in response to air puffing, resulting in a dual optical signal in the mechnoluminescence (ML) soft composite. Nature Publishing Group UK 2019-10-23 /pmc/articles/PMC6811554/ /pubmed/31645632 http://dx.doi.org/10.1038/s41598-019-51771-z Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Kim, Yooil
Roy, Sunanda
Jung, Gwang-Yong
Oh, Jung-Sik
Kim, Gi-Woo
Dual Optical Signal-based Intraocular Pressure-sensing Principle Using Pressure-sensitive Mechanoluminescent ZnS:Cu/PDMS Soft Composite
title Dual Optical Signal-based Intraocular Pressure-sensing Principle Using Pressure-sensitive Mechanoluminescent ZnS:Cu/PDMS Soft Composite
title_full Dual Optical Signal-based Intraocular Pressure-sensing Principle Using Pressure-sensitive Mechanoluminescent ZnS:Cu/PDMS Soft Composite
title_fullStr Dual Optical Signal-based Intraocular Pressure-sensing Principle Using Pressure-sensitive Mechanoluminescent ZnS:Cu/PDMS Soft Composite
title_full_unstemmed Dual Optical Signal-based Intraocular Pressure-sensing Principle Using Pressure-sensitive Mechanoluminescent ZnS:Cu/PDMS Soft Composite
title_short Dual Optical Signal-based Intraocular Pressure-sensing Principle Using Pressure-sensitive Mechanoluminescent ZnS:Cu/PDMS Soft Composite
title_sort dual optical signal-based intraocular pressure-sensing principle using pressure-sensitive mechanoluminescent zns:cu/pdms soft composite
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811554/
https://www.ncbi.nlm.nih.gov/pubmed/31645632
http://dx.doi.org/10.1038/s41598-019-51771-z
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