SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells

Adolescent idiopathic scoliosis (AIS) is a complex, three-dimensional deformity of the spine that commonly occurs in pubescent girls. Decreased osteogenic differentiation and aberrant melatonin signalling have been demonstrated in mesenchymal stem cells (MSCs) from AIS patients and are implicated in...

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Detalles Bibliográficos
Autores principales: Li, Jing, Li, Na, Chen, Yunfei, Hui, Shangyi, Fan, Junfen, Ye, Buqing, Fan, Zusen, Zhang, Jianguo, Zhao, Robert Chunhua, Zhuang, Qianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811559/
https://www.ncbi.nlm.nih.gov/pubmed/31645544
http://dx.doi.org/10.1038/s41419-019-1949-7

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