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Multi-tissue network analysis for drug prioritization in knee osteoarthritis

Knee osteoarthritis (OA) is a joint disease that affects several tissues: cartilage, synovium, meniscus and subchondral bone. The pathophysiology of this complex disease is still not completely understood and existing pharmaceutical strategies are limited to pain relief treatments. Therefore, a comp...

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Detalles Bibliográficos
Autores principales: Neidlin, Michael, Dimitrakopoulou, Smaragda, Alexopoulos, Leonidas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811565/
https://www.ncbi.nlm.nih.gov/pubmed/31645614
http://dx.doi.org/10.1038/s41598-019-51627-6