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Tracking genome-editing and associated molecular perturbations by SWATH mass spectrometry

Advances in gene editing now allow reverse genetics to be applied to a broad range of biological systems. Ultimately, any modification to coding sequences requires confirmation at the protein level, although immunoblotting is often hampered by antibody quality or availability especially in non-model...

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Detalles Bibliográficos
Autores principales: Lin, Qifeng, Low, Larry W. L., Lau, Adam, Chua, Esther W. L., Matsuoka, Yuji, Lian, Yilong, Monteiro, Antónia, Tate, Stephen, Gunaratne, Jayantha, Carney, Tom J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811567/
https://www.ncbi.nlm.nih.gov/pubmed/31645615
http://dx.doi.org/10.1038/s41598-019-51612-z

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