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Regulatory Crosstalk of Doxorubicin, Estradiol and TNFα Combined Treatment in Breast Cancer-derived Cell Lines

We present a new model of ESR1 network regulation based on analysis of Doxorubicin, Estradiol, and TNFα combination treatment in MCF-7. We used Doxorubicin as a therapeutic agent, TNFα as marker and mediator of an inflammatory microenvironment and 17β-Estradiol (E2) as an agonist of Estrogen Recepto...

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Detalles Bibliográficos
Autores principales:	Nassiri, Isar, Inga, Alberto, Meškytė, Erna Marija, Alessandrini, Federica, Ciribilli, Yari, Priami, Corrado
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811586/ https://www.ncbi.nlm.nih.gov/pubmed/31645610 http://dx.doi.org/10.1038/s41598-019-51349-9

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