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Affective Features Underlying Depression in Addiction: Understanding What It Feels Like

Addiction poses a complex challenge in spite of all the progress made toward understanding and treating it. A multidisciplinary approach is needed and this paper attempts to integrate relevant neurobiological, behavioral, and subjective data under a common denominator described as a latent type of d...

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Autor principal: Flores Mosri, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811663/
https://www.ncbi.nlm.nih.gov/pubmed/31681110
http://dx.doi.org/10.3389/fpsyg.2019.02318
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author Flores Mosri, Daniela
author_facet Flores Mosri, Daniela
author_sort Flores Mosri, Daniela
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description Addiction poses a complex challenge in spite of all the progress made toward understanding and treating it. A multidisciplinary approach is needed and this paper attempts to integrate relevant neurobiological, behavioral, and subjective data under a common denominator described as a latent type of depression. It is called latent because it remains a silent syndrome due to two main reasons. The first one relates to the natural use of defenses against a predominant effect of chronic subjective pain, which arises from an ambivalent type of separation distress that compromises opioid regulation (PANIC system). Furthermore, it provokes a neurochemical cascade that impacts several neuromodulatory systems. The second reason is that such chronic subjective pain usually exhausts the natural defensive system, frequently leading the person to look for other resources such as the neurochemical manipulation of psychic pain. Thus, both the use of defenses and of psychotoxic drugs make the underlying depression hard to assess, even for the very person suffering from it. The causes, course and treatment of this type of affective configuration are discussed in this paper as an attempt to explain some of the difficulties so far encountered and to contribute to potential alternative lines of treatment.
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spelling pubmed-68116632019-11-01 Affective Features Underlying Depression in Addiction: Understanding What It Feels Like Flores Mosri, Daniela Front Psychol Psychology Addiction poses a complex challenge in spite of all the progress made toward understanding and treating it. A multidisciplinary approach is needed and this paper attempts to integrate relevant neurobiological, behavioral, and subjective data under a common denominator described as a latent type of depression. It is called latent because it remains a silent syndrome due to two main reasons. The first one relates to the natural use of defenses against a predominant effect of chronic subjective pain, which arises from an ambivalent type of separation distress that compromises opioid regulation (PANIC system). Furthermore, it provokes a neurochemical cascade that impacts several neuromodulatory systems. The second reason is that such chronic subjective pain usually exhausts the natural defensive system, frequently leading the person to look for other resources such as the neurochemical manipulation of psychic pain. Thus, both the use of defenses and of psychotoxic drugs make the underlying depression hard to assess, even for the very person suffering from it. The causes, course and treatment of this type of affective configuration are discussed in this paper as an attempt to explain some of the difficulties so far encountered and to contribute to potential alternative lines of treatment. Frontiers Media S.A. 2019-10-17 /pmc/articles/PMC6811663/ /pubmed/31681110 http://dx.doi.org/10.3389/fpsyg.2019.02318 Text en Copyright © 2019 Flores Mosri. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Flores Mosri, Daniela
Affective Features Underlying Depression in Addiction: Understanding What It Feels Like
title Affective Features Underlying Depression in Addiction: Understanding What It Feels Like
title_full Affective Features Underlying Depression in Addiction: Understanding What It Feels Like
title_fullStr Affective Features Underlying Depression in Addiction: Understanding What It Feels Like
title_full_unstemmed Affective Features Underlying Depression in Addiction: Understanding What It Feels Like
title_short Affective Features Underlying Depression in Addiction: Understanding What It Feels Like
title_sort affective features underlying depression in addiction: understanding what it feels like
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811663/
https://www.ncbi.nlm.nih.gov/pubmed/31681110
http://dx.doi.org/10.3389/fpsyg.2019.02318
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