Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action

Sialic acids are a family of related sugars that play essential roles in many biological events intimately linked to cellular recognition in both health and disease. Sialidases are therefore orchestrators of cellular biology and important therapeutic targets for viral infection. Here, we sought to d...

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Detalles Bibliográficos
Autores principales: Bule, Pedro, Chuzel, Léa, Blagova, Elena, Wu, Liang, Gray, Melissa A., Henrissat, Bernard, Rapp, Erdmann, Bertozzi, Carolyn R., Taron, Christopher H., Davies, Gideon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811678/
https://www.ncbi.nlm.nih.gov/pubmed/31645552
http://dx.doi.org/10.1038/s41467-019-12684-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811678/
https://www.ncbi.nlm.nih.gov/pubmed/31645552
http://dx.doi.org/10.1038/s41467-019-12684-7

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