Cargando…

Intranasal administration of a stapled relaxin‐3 mimetic has anxiolytic‐ and antidepressant‐like activity in rats

BACKGROUND AND PURPOSE: Depression and anxiety are common causes of disability, and innovative tools and potential pharmacological targets are actively sought for prevention and treatment. Therapeutic strategies targeting the relaxin‐3 peptide or its primary endogenous receptor, RXFP3, for the treat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marwari, Subhi, Poulsen, Anders, Shih, Norrapat, Lakshminarayanan, Rajamani, Kini, R. Manjunatha, Johannes, Charles William, Dymock, Brian William, Dawe, Gavin Stewart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811745/ https://www.ncbi.nlm.nih.gov/pubmed/31220339 http://dx.doi.org/10.1111/bph.14774

Ejemplares similares

Relaxin’ the brain: a case for targeting the nucleus incertus network and relaxin‐3/RXFP3 system in neuropsychiatric disorders
por: Kumar, Jigna Rajesh, et al.
Publicado: (2016)

Antidepressants, anxiolytics, and hypnotics in pregnancy and lactation
por: Ram, Daya, et al.
Publicado: (2015)

Anxiolytic Action of Taurine via Intranasal Administration in Mice
por: Jung, Jung Hwa, et al.
Publicado: (2019)

Nanosystems, Drug Molecule Functionalization and Intranasal Delivery: An Update on the Most Promising Strategies for Increasing the Therapeutic Efficacy of Antidepressant and Anxiolytic Drugs
por: Antunes, Jéssica L., et al.
Publicado: (2023)

The Role of Pharmacogenetics in Personalizing the Antidepressant and Anxiolytic Therapy
por: Radosavljevic, Milica, et al.
Publicado: (2023)

Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides
por: Pal, Arumay, et al.
Publicado: (2019)

ANXIETY AND DEPRESSIVE NEUROSIS - THEIR RESPONSE TO ANXIOLYTIC AND ANTIDEPRESSANT TREATMENT
por: Singh, Gurmeet, et al.
Publicado: (1987)

Antidepressant and Anxiolytic Potentials of the Chewing Stick, Salvadora persica
por: Vasudevan, Rajalakshimi, et al.
Publicado: (2023)

Rational Optimization of Conformational Effects Induced By Hydrocarbon Staples in Peptides and their Binding Interfaces
por: Lama, Dilraj, et al.
Publicado: (2013)

Evaluation of Antidepressant and Anxiolytic Activity of Phosphodiesterase 3 Inhibitor - Cilostazol
por: Patel, Dipesh S., et al.
Publicado: (2012)

Examining the short-term anxiolytic and antidepressant effect of Floatation-REST
por: Feinstein, Justin S., et al.
Publicado: (2018)

Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond
por: Zorumski, Charles F., et al.
Publicado: (2019)

Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial
por: Martin, Erin L., et al.
Publicado: (2021)

Anxiolytic and antidepressant potential of extracts of Duchesnea Indica in animal models
por: Mohibullah,, et al.
Publicado: (2022)

Relaxin'
Publicado: (1983)

Relaxin
por: DeCherney, Alan H.
Publicado: (1982)

Exploring pharmacological inhibition of G(q/11) as an analgesic strategy
por: Marwari, Subhi, et al.
Publicado: (2022)

Antidepressive and anxiolytic effects of ostruthin, a TREK-1 channel activator
por: Joseph, Ancy, et al.
Publicado: (2018)

Antidepressant, Anxiolytic and Neuroprotective Activities of Two Zinc Compounds in Diabetic Rats
por: Cavalcanti, Christiane Leite, et al.
Publicado: (2020)

Exogenous Carbon Monoxide Produces Rapid Antidepressant- and Anxiolytic-Like Effects
por: Luo, Yixiao, et al.
Publicado: (2021)

Anxiolytic and Antidepressant Use and Burnout: Optimism as a Mediator in Spanish Nurses
por: Martos Martínez, África, et al.
Publicado: (2021)

Anxiolytic and antidepressants’ effect of Crataegus pinnatifida (Shan Zha): biochemical mechanisms
por: Nitzan, Keren, et al.
Publicado: (2022)

Anxiolytic, antidepressant and antioxidant activity of the methanol extract of Canarium resiniferum leaves
por: Shah, Md Shahin, et al.
Publicado: (2022)

Antidepressant and Anxiolytic Effects of Fermented Huauzontle, a Prehispanic Mexican Pseudocereal
por: Santiago-López, Lourdes, et al.
Publicado: (2022)

Utilization of antidepressants, anxiolytics, and hypnotics during the COVID-19 pandemic in Scandinavia
por: Tiger, Mikael, et al.
Publicado: (2023)

Anxiolytic and Antidepressant Potential of Methanolic Extract of Neurada procumbens Linn. in Mice
por: Khalid, Ahmed Awais, et al.
Publicado: (2023)

Antihypernociceptive, Anxiolytic, and Antidepressant Properties of Aqueous and Ethanol Extracts of Dissotis thollonii Cogn. (Melastomataceae) in Mice
por: Djuichou Nguemnang, Stephanie Flore, et al.
Publicado: (2020)

CT-Screening for lung cancer does not increase the use of anxiolytic or antidepressant medication
por: Kaerlev, Linda, et al.
Publicado: (2012)

Anxiolytic and Antidepressant Effects of Maerua angolensis DC. Stem Bark Extract in Mice
por: Benneh, Charles Kwaku, et al.
Publicado: (2018)

Anxiolytic-like and antidepressant-like effects of ethanol extract of Terminalia chebula in mice()
por: Mani, Vasudevan, et al.
Publicado: (2021)

Antispasmodic, antidepressant and anxiolytic effects of extracts from Schinus lentiscifolius Marchand leaves
por: Vanegas Andrade, Catalina, et al.
Publicado: (2021)

Higher prescription of antidepressants and/or anxiolytics among chronic obstructive pulmonary disease patients
por: Pelgrim, Charlotte E., et al.
Publicado: (2021)

Methylone, a rapid acting entactogen with robust anxiolytic and antidepressant-like activity
por: Warner-Schmidt, Jennifer, et al.
Publicado: (2023)

Design and Application in Delivery System of Intranasal Antidepressants
por: Xu, Jingying, et al.
Publicado: (2020)

Enhancing Spatial Memory: Anxiolytic and Antidepressant Effects of Tapinanthus dodoneifolius (DC) Danser in Mice
por: Harquin Simplice, Foyet, et al.
Publicado: (2014)

Anxiolytic and Antidepressant-Like Effects of the Aqueous Extract of Alafia multiflora Stem Barks in Rodents
por: Foyet, Harquin Simplice, et al.
Publicado: (2012)

Antidepressant, anxiolytic and procognitive effects of rivastigmine and donepezil in the chronic mild stress model in rats
por: Papp, Mariusz, et al.
Publicado: (2016)

Anxiolytic, antidepressant, and antistress activities of the aqueous extract of Cinnamomum tamala Nees and Eberm in rats
por: Upadhyay, Gayaprasad, et al.
Publicado: (2016)

Role of Monoaminergic System in the Etiology of Olive Oil Induced Antidepressant and Anxiolytic Effects in Rats
por: Perveen, Tahira, et al.
Publicado: (2013)

Disinhibition of somatostatin-positive GABAergic interneurons results in an anxiolytic and antidepressant-like brain state
por: Fuchs, T, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_q1phvdseqtqfidrqauooclqbf9