Cytokines trigger disruption of endothelium barrier function and p38 MAP kinase activation in BMPR2-silenced human lung microvascular endothelial cells

The bone morphogenetic protein receptor II (BMPRII) signaling pathway is impaired in pulmonary arterial hypertension and mutations in the BMPR2 gene have been observed in both heritable and idiopathic pulmonary arterial hypertension. However, all BMPR2 mutation carriers do not develop pulmonary arte...

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Detalles Bibliográficos
Autores principales: Tielemans, Birger, Stoian, Leanda, Gijsbers, Rik, Michiels, Annelies, Wagenaar, Allard, Farre Marti, Ricard, Belge, Catharina, Delcroix, Marion, Quarck, Rozenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811766/
https://www.ncbi.nlm.nih.gov/pubmed/31692724
http://dx.doi.org/10.1177/2045894019883607

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