Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer's Disease

In Alzheimer's disease (AD), tau pathology manifested by the accumulation of intraneuronal tangles and soluble toxic oligomers emerges as a promising therapeutic target. Multiple anti-tau antibodies inhibiting the formation and propagation of cytotoxic tau or promoting its clearance and degrada...

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Detalles Bibliográficos
Autores principales: Hromadkova, Lenka, Ovsepian, Saak Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811779/
https://www.ncbi.nlm.nih.gov/pubmed/31687413
http://dx.doi.org/10.1155/2019/7406810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811779/
https://www.ncbi.nlm.nih.gov/pubmed/31687413
http://dx.doi.org/10.1155/2019/7406810

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