Cargando…

AMBRA1, Autophagy, and the Extreme Male Brain Theory of Autism

The extreme male brain theory of autism posits that its male bias is mediated by exaggeration of male-biased sex differences in the expression of autism-associated traits found in typical populations. The theory is supported by extensive phenotypic evidence, but no genes have yet been described with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crespi, Bernard, Read, Silven, Ly, Amy, Hurd, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811796/ https://www.ncbi.nlm.nih.gov/pubmed/31687209 http://dx.doi.org/10.1155/2019/1968580

Ejemplares similares

Spirituality, dimensional autism, and schizotypal traits: The search for meaning
por: Crespi, Bernard, et al.
Publicado: (2019)

Cognitive Empathy as Imagination: Evidence From Reading the Mind in the Eyes in Autism and Schizotypy
por: Nahal, Priya, et al.
Publicado: (2021)

SHANK3 Genotype Mediates Speech and Language Phenotypes in a Nonclinical Population
por: Manning, Christina, et al.
Publicado: (2021)

Do the diverse phenotypes of Prader-Willi syndrome reflect extremes of covariation in typical populations?
por: Salminen, Iiro, et al.
Publicado: (2022)

Ambra1 Is an Essential Regulator of Autophagy and Apoptosis in SW620 Cells: Pro-Survival Role of Ambra1
por: Gu, Wen, et al.
Publicado: (2014)

mTOR, AMBRA1, and autophagy: An intricate relationship
por: Nazio, Francesca, et al.
Publicado: (2013)

Connecting autophagy: AMBRA1 and its network of regulation
por: Cianfanelli, Valentina, et al.
Publicado: (2015)

The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone
por: Yazdankhah, M, et al.
Publicado: (2014)

Ambra Grisea
por: Still, Horace
Publicado: (1888)

Zebrafish ambra1a and ambra1b Knockdown Impairs Skeletal Muscle Development
por: Skobo, Tatjana, et al.
Publicado: (2014)

Ambra1 induces autophagy and desensitizes human prostate cancer cells to cisplatin
por: Liu, Jie, et al.
Publicado: (2019)

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
por: Di Bartolomeo, Sabrina, et al.
Publicado: (2010)

RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy
por: Xia, Pengyan, et al.
Publicado: (2014)

Correction: Zebrafish ambra1a and ambra1b Knockdown Impairs Skeletal Muscle Development
Publicado: (2014)

Autophagy and apoptosis are regulated by stress on Bcl2 by AMBRA1 in the endoplasmic reticulum and mitochondria
por: Yang, Bojie, et al.
Publicado: (2019)

AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-MYC dephosphorylation and degradation
por: Cianfanelli, Valentina, et al.
Publicado: (2014)

Ambra1 modulates the sensitivity of breast cancer cells to epirubicin by regulating autophagy via ATG12
por: Sun, Wei‐Liang, et al.
Publicado: (2018)

AMBRA1 attenuates the proliferation of uveal melanoma cells
por: Zhao, Binbin, et al.
Publicado: (2021)

Loss of Ambra1 promotes melanoma growth and invasion
por: Di Leo, Luca, et al.
Publicado: (2021)

Ambra1 deficiency impairs mitophagy in skeletal muscle
por: Gambarotto, Lisa, et al.
Publicado: (2022)

Heterozygous Ambra1 Deficiency in Mice: A Genetic Trait with Autism-Like Behavior Restricted to the Female Gender
por: Dere, Ekrem, et al.
Publicado: (2014)

Zebrafish ambra1b knockout reveals a novel role for Ambra1 in primordial germ cells survival, sex differentiation and reproduction
por: Fontana, Camilla Maria, et al.
Publicado: (2023)

AMBRA1 and SQSTM1 expression pattern in prostate cancer
por: Falasca, Laura, et al.
Publicado: (2015)

Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling
por: Nazio, Francesca, et al.
Publicado: (2021)

Testing the Empathizing–Systemizing theory of sex differences and the Extreme Male Brain theory of autism in half a million people
por: Greenberg, David M., et al.
Publicado: (2018)

AMBRA1 and its role as a target for anticancer therapy
por: Li, Xiang, et al.
Publicado: (2022)

How Are Autism and Schizotypy Related? Evidence from a Non-Clinical Population
por: Dinsdale, Natalie L., et al.
Publicado: (2013)

Ambras Syndrome with Gingival Hyperplasia: A Rare Entity
por: Reddy Kundoor, Vinay Kumar, et al.
Publicado: (2016)

Sexual dimorphism of AMBRA1-related autistic features in human and mouse
por: Mitjans, M, et al.
Publicado: (2017)

AMBRA1-induced mitophagy: A new mechanism to cope with cancer?
por: Strappazzon, Flavie, et al.
Publicado: (2015)

Effects of caloric restriction on neuropathic pain, peripheral nerve degeneration and inflammation in normometabolic and autophagy defective prediabetic Ambra1 mice
por: Coccurello, Roberto, et al.
Publicado: (2018)

Ambra1 Alleviates Hypoxia/Reoxygenation Injury in H9C2 Cells by Regulating Autophagy and Reactive Oxygen Species
por: Zhao, Lin, et al.
Publicado: (2020)

HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1
por: Antonioli, Manuela, et al.
Publicado: (2020)

MiR-3653 blocks autophagy to inhibit epithelial–mesenchymal transition in breast cancer cells by targeting the autophagy-regulatory genes ATG12 and AMBRA1
por: Song, Huachen, et al.
Publicado: (2023)

AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation
por: Faienza, Fiorella, et al.
Publicado: (2023)

Ambra1 Shapes Hippocampal Inhibition/Excitation Balance: Role in Neurodevelopmental Disorders
por: Nobili, Annalisa, et al.
Publicado: (2018)

Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma
por: Frias, Alex, et al.
Publicado: (2023)

The hallmarks of autism
por: Crespi, Bernard J.
Publicado: (2022)

Pattern Unifies Autism
por: Crespi, Bernard
Publicado: (2021)

Prolonged Pseudohypoxia Targets Ambra1 mRNA to P-Bodies for Translational Repression
por: Pourpirali, Somayeh, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_si5fmm6rtfetcdl2frm49agph9