Cargando…

Novel Hydrophilic Copolymer-Based Nanoparticle Enhances the Therapeutic Efficiency of Doxorubicin in Cultured MCF-7 Cells

[Image: see text] Nanoparticle drug delivery applications have predominantly focused on the entrapment and delivery of hydrophobic molecules with poor water solubility. However, benefits can also be obtained from nanoparticle-based delivery of hydrophilic therapeutics. This study reports on the deve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naidu, Priya S. R., Norret, Marck, Dunlop, Sarah A., Fitzgerald, Melinda, Clemons, Tristan D., Iyer, K. Swaminathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811859/ https://www.ncbi.nlm.nih.gov/pubmed/31656880 http://dx.doi.org/10.1021/acsomega.8b02894

Ejemplares similares

Protein corona formation moderates the release kinetics of ion channel antagonists from transferrin-functionalized polymeric nanoparticles
por: Naidu, Priya S. R., et al.
Publicado: (2020)

An Unexpected Transient Breakdown of the Blood Brain Barrier Triggers Passage of Large Intravenously Administered Nanoparticles
por: Smith, Nicole M., et al.
Publicado: (2016)

Biodegradable Copolymer for Stimuli-Responsive Sustained Release of Doxorubicin
por: Bhattacharya, Sayantani, et al.
Publicado: (2016)

Characterization of polymeric nanoparticles for treatment of partial injury to the central nervous system
por: Lozić, Ivan, et al.
Publicado: (2016)

Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation
por: Ho, Diwei, et al.
Publicado: (2017)

Development of Double Hydrophilic Block Copolymer/Porphyrin Polyion Complex Micelles towards Photofunctional Nanoparticles
por: Karayianni, Maria, et al.
Publicado: (2022)

Discovery of Novel Doxorubicin Metabolites in MCF7 Doxorubicin-Resistant Cells
por: Wang, Xu, et al.
Publicado: (2019)

Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles
por: Morys, Stephan, et al.
Publicado: (2017)

Magnetic nanoparticles sensitize MCF-7 breast cancer cells to doxorubicin-induced apoptosis
por: Aljarrah, Khaled, et al.
Publicado: (2012)

Hydrophilic Random Cationic Copolymers as Polyplex-Formation Vectors for DNA
por: Chrysostomou, Varvara, et al.
Publicado: (2022)

Hydrophilic mesoporous carbon nanospheres with high drug-loading efficiency for doxorubicin delivery and cancer therapy
por: Wang, Huan, et al.
Publicado: (2016)

Lipid-polymer hybrid nanoparticles for controlled delivery of hydrophilic and lipophilic doxorubicin for breast cancer therapy
por: Tahir, Nayab, et al.
Publicado: (2019)

Corrigendum: Discovery of Novel Doxorubicin Metabolites in MCF7 Doxorubicin-Resistant Cells
por: Wang, Xu, et al.
Publicado: (2020)

Lipid-Polymer Hybrid Nanoparticles for Controlled Delivery of Hydrophilic and Lipophilic Doxorubicin for Breast Cancer Therapy [Erratum]
Publicado: (2020)

Polyelectrolyte Complexation of Oligonucleotides by Charged Hydrophobic—Neutral Hydrophilic Block Copolymers
por: Marras, Alexander E., et al.
Publicado: (2019)

New Copolymers of Vinylphosphonic Acid with Hydrophilic Monomers and Their Eu(3+) Complexes
por: Nazarova, Olga, et al.
Publicado: (2022)

A facile methodology using quantum dot multiplex labels for tracking co-transfection
por: Kretzmann, Jessica A., et al.
Publicado: (2019)

Hydrophilic Polyester Microspheres: Effect of Molecular Weight and Copolymer Composition on Release of BSA
por: Ghassemi, Amir H., et al.
Publicado: (2010)

Hydrophilization of Poly(Caprolactone) Copolymers through Introduction of Oligo(Ethylene Glycol) Moieties
por: Wurth, Jonathan J., et al.
Publicado: (2014)

Considerations in binding diblock copolymers on hydrophilic alginate beads for providing an immunoprotective membrane
por: Spasojevic, Milica, et al.
Publicado: (2014)

Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine
por: Komoto, Kana, et al.
Publicado: (2020)

Synthesis, characterization and properties of a novel environmentally friendly ternary hydrophilic copolymer
por: Ma, Wentao, et al.
Publicado: (2023)

Surface Stiffness Has No Impact on MCF-7 Sensitivity to Doxorubicin
por: Šimoliūnas, Egidijus, et al.
Publicado: (2023)

Protonation-Induced Microphase Separation in Thin Films of a Polyelectrolyte-Hydrophilic Diblock Copolymer
por: Stewart-Sloan, Charlotte R., et al.
Publicado: (2014)

Amphiphilic diblock copolymer of hydrophilic-functionalized lactone and lactide via switchable organocatalytic polymerization
por: Bai, Jinmei, et al.
Publicado: (2018)

Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells
por: Srdic-Rajic, Tatjana, et al.
Publicado: (2017)

Effects of folic acid on the antiproliferative efficiency of doxorubicin, camptothecin and methyl methanesulfonate in MCF-7 cells by mRNA endpoints
por: Xavier, Muriel Almeida, et al.
Publicado: (2018)

Cinnamaldehyde and Doxorubicin Co-Loaded Graphene Oxide Wrapped Mesoporous Silica Nanoparticles for Enhanced MCF-7 Cell Apoptosis
por: Dong, Kai, et al.
Publicado: (2020)

Preparation and in vitro evaluation of doxorubicin-loaded Fe3O4 magnetic nanoparticles modified with biocompatible copolymers
por: Akbarzadeh, Abolfazl, et al.
Publicado: (2012)

Altered Surface Hydrophilicity on Copolymer Scaffolds Stimulate the Osteogenic Differentiation of Human Mesenchymal Stem Cells
por: Xing, Zhe, et al.
Publicado: (2020)

Dual Reduction/Acid-Responsive Disassembly and Thermoresponsive Tunability of Degradable Double Hydrophilic Block Copolymer
por: Maruya-Li, Keaton, et al.
Publicado: (2020)

Hydrophilic Cross-Linked Aliphatic Hydrocarbon Diblock Copolymer as Proton Exchange Membrane for Fuel Cells
por: Julius, David, et al.
Publicado: (2021)

Effect of hydrophilic block end groups and block junction on block copolymer self-assembly in solution
por: Ha, Sungmin, et al.
Publicado: (2022)

Formation of Hydrophobic–Hydrophilic Associates in the N-Vinylpyrrolidone and Vinyl Propyl Ether Copolymer Aqueous Solutions
por: Kabdushev, Sherniyaz, et al.
Publicado: (2023)

Hydrophilic Copolymers with Hydroxamic Acid Groups as a Protective Biocompatible Coating of Maghemite Nanoparticles: Synthesis, Physico-Chemical Characterization and MRI Biodistribution Study
por: Charvátová, Hana, et al.
Publicado: (2023)

Poly (I:C)- and doxorubicin-loaded magnetic dendrimeric nanoparticles affect the apoptosis-related gene expressions in MCF-7 cells
por: KHODADUST, Rouhollah, et al.
Publicado: (2020)

Rational design of multifunctional micelles against doxorubicin-sensitive and doxorubicin-resistant MCF-7 human breast cancer cells
por: Hong, Wei, et al.
Publicado: (2017)

Combined effect of papuamine and doxorubicin in human breast cancer MCF-7 cells
por: KANNO, SYU-ICHI, et al.
Publicado: (2014)

Cholesterol Dependent Uptake and Interaction of Doxorubicin in MCF-7 Breast Cancer Cells
por: Weber, Petra, et al.
Publicado: (2013)

The Cytotoxic and Antimigratory Activity of Brazilin-Doxorubicin on MCF-7/HER2 Cells
por: Jenie, Riris Istighfari, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_75l43lge9s9tpjs1qu19tt9to6