Synthetic Approach to the ABCD Ring System of Anticancer Agent Fredericamycin A via Claisen Rearrangement and Ring-Closing Metathesis as Key Steps

[Image: see text] A new synthetic strategy to the ABCD ring system of the anticancer agent fredericamycin A (NSC-305263) was realized by the Diels–Alder reaction and olefin metathesis as key steps. The tactics developed here for the construction of the ABCD ring system also involve double Claisen re...

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Detalles Bibliográficos
Autores principales: Kotha, Sambasivarao, Cheekatla, Subba Rao, Fatma, Ambareen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811863/
https://www.ncbi.nlm.nih.gov/pubmed/31656883
http://dx.doi.org/10.1021/acsomega.9b01178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811863/
https://www.ncbi.nlm.nih.gov/pubmed/31656883
http://dx.doi.org/10.1021/acsomega.9b01178

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