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Data on left ventricular expression of STAT3 and AKT in transgenic mouse models with B16F10 melanoma
The dataset describes protein expression of phosphorylated and total signal transducer and activator of transcription 3 (STAT3), protein kinase B (AKT) and suppressor of cytokine signalling 3 (SOCS3) in left ventricular tissue (LV) from healthy and B16F10 melanoma tumour-bearing (B16F10-TM) wildtype...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811954/ https://www.ncbi.nlm.nih.gov/pubmed/31667271 http://dx.doi.org/10.1016/j.dib.2019.104508 |
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author | Pietzsch, Stefan Ricke-Hoch, Melanie Stapel, Britta Hilfiker-Kleiner, Denise |
author_facet | Pietzsch, Stefan Ricke-Hoch, Melanie Stapel, Britta Hilfiker-Kleiner, Denise |
author_sort | Pietzsch, Stefan |
collection | PubMed |
description | The dataset describes protein expression of phosphorylated and total signal transducer and activator of transcription 3 (STAT3), protein kinase B (AKT) and suppressor of cytokine signalling 3 (SOCS3) in left ventricular tissue (LV) from healthy and B16F10 melanoma tumour-bearing (B16F10-TM) wildtype (WT) mice, mice with cardiomyocyte-specific constitutively active AKT transgene (AKTtg) and mice with cardiomyocyte-restricted deletion of STAT3 (CKO) analysed in Western blot and/or fluorescence microscopy experiments. The data presented in this article are related to the research paper entitled “Modulation of cardiac AKT and STAT3 signalling in preclinical cancer models and their impact on the heart”, available in Biochim. Biophys. Acta Mol. Cell Res. (1). |
format | Online Article Text |
id | pubmed-6811954 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-68119542019-10-30 Data on left ventricular expression of STAT3 and AKT in transgenic mouse models with B16F10 melanoma Pietzsch, Stefan Ricke-Hoch, Melanie Stapel, Britta Hilfiker-Kleiner, Denise Data Brief Biochemistry, Genetics and Molecular Biology The dataset describes protein expression of phosphorylated and total signal transducer and activator of transcription 3 (STAT3), protein kinase B (AKT) and suppressor of cytokine signalling 3 (SOCS3) in left ventricular tissue (LV) from healthy and B16F10 melanoma tumour-bearing (B16F10-TM) wildtype (WT) mice, mice with cardiomyocyte-specific constitutively active AKT transgene (AKTtg) and mice with cardiomyocyte-restricted deletion of STAT3 (CKO) analysed in Western blot and/or fluorescence microscopy experiments. The data presented in this article are related to the research paper entitled “Modulation of cardiac AKT and STAT3 signalling in preclinical cancer models and their impact on the heart”, available in Biochim. Biophys. Acta Mol. Cell Res. (1). Elsevier 2019-09-18 /pmc/articles/PMC6811954/ /pubmed/31667271 http://dx.doi.org/10.1016/j.dib.2019.104508 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Biochemistry, Genetics and Molecular Biology Pietzsch, Stefan Ricke-Hoch, Melanie Stapel, Britta Hilfiker-Kleiner, Denise Data on left ventricular expression of STAT3 and AKT in transgenic mouse models with B16F10 melanoma |
title | Data on left ventricular expression of STAT3 and AKT in transgenic mouse models with B16F10 melanoma |
title_full | Data on left ventricular expression of STAT3 and AKT in transgenic mouse models with B16F10 melanoma |
title_fullStr | Data on left ventricular expression of STAT3 and AKT in transgenic mouse models with B16F10 melanoma |
title_full_unstemmed | Data on left ventricular expression of STAT3 and AKT in transgenic mouse models with B16F10 melanoma |
title_short | Data on left ventricular expression of STAT3 and AKT in transgenic mouse models with B16F10 melanoma |
title_sort | data on left ventricular expression of stat3 and akt in transgenic mouse models with b16f10 melanoma |
topic | Biochemistry, Genetics and Molecular Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811954/ https://www.ncbi.nlm.nih.gov/pubmed/31667271 http://dx.doi.org/10.1016/j.dib.2019.104508 |
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